Antihypertensive drugs are used to prevent and manage hypertension. These medications help to prevent the complications of high blood pressure, such as stroke and myocardial infarction.
The calcium channel blockers are cardiovascular drugs that inhibit the L-type calcium channels to lower blood pressure. They work by decreasing the movement of calcium into the cells of the heart and blood vessel walls, making it easier for the heart to pump and widen blood vessels.
Beta-blockers such as β-Adrenoceptor antagonists are recommended for the first-line treatment for high blood pressure by blocking the effects of the adrenaline hormone. As a result, the heart beats with less force leading to improved blood flow.
Angiotensin II receptor blockers (ARB) act by blocking the effect of angiotensin II to widen blood vessels. Clinical evidence suggests that this action mechanism has benefits beyond blood pressure (BP) control and is now said to have a CV, cerebral, and renal protective effects.
Ivabradine is a heart-rate-lowering agent used when the heart is unable to pump enough blood to the other parts of the body. It inhibits the cardiac pacemaker current (If) to regulate the heart rate and to pump more blood through the body for each heartbeat.